![]() The treatment begins within the first 5 days of stroke and is maintained for 6 months. Patients will be randomized into four arms: 1) control group, 2) treatment with citalopram 20 mg / day, 3) group levodopa (sinemet plus)100 mg / day, 4) group levodopa (sinemet plus) 100 mg / day + citalopram 20 mg / day. Evaluate 240 consecutive patients with a first ischemic stroke with NIHSS 5-20 without aphasia and with a previous independent functional status (mRS <3). Study Primary Completion Date: March 2017.Intervention Model: Parallel Assignment.In a pilot study, will evaluate the potential benefit of drugs that increase the release of neurotransmitters in patients with first stroke.įull Title of Study: “Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction” Study Type Neurotransmitter release, facilitates the creation of new synapses and promotes brain plasticity. Cortical plasticity plays a pivotal role in functional recovery after a stroke.
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